Enzogenol, The High Dose Flavonoid Antioxidant Formula

What is Enzogenol

Enzogenol is a 100% natural extract from the bark of New Zealand grown Pinus radiata trees. The pines are plantation grown in New Zealand’s pristine environment where this species finds ideal growing conditions. New Zealand’s vast pine forests are managed on an environmentally sustainable basis. Through long standing close relationships with our suppliers we ensure high quality raw material supply.

The pines grow for 25-30 years before felling. The bark is then harvested from the lower third of the mature tree trunk. This guarantees a homogeneous starting material and contributes to the guaranteed quality of the Enzogenol composition. The uniform age of the trees and choice of bark ensures consistency in the starting material and thereby minimizes any variation in the compounds extracted from the bark.


Process Flow Diagram

Extraction Method to make Enzogenol from Pine Bark

Enzogenol is produced using ENZO Nutraceuticals’ proprietary, internationally patented pure water extraction technology. The process was developed by a multi-disciplinary team of researchers and engineers, and combines several important advantages:

  • Pure Water Process – The extraction uses only pure, deionised water, no solvents, chemicals, or additives of any sort are used in the process eliminating any possibility of unwanted residues.
  • Full polyphenol compound spectrum – The process produces a 100% natural extract from the pine bark that contains the full spectrum of health beneficial polyphenolic compounds present in the bark.
  • Protecting maximal activity – The extraction conditions are optimised to protect the natural state of the polyphenols preserving the maximal anti-oxidant, and anti-inflammatory activities.
  • Ecologically sound technology – The entire process is environmentally friendly and does not produce any problematic wastes.

Compounds in Enzogenol

Enzogenol is a complex mixture of plant phenolic compounds including many different flavonoids and phenolic acids that occur naturally in the pine bark and function as natural antioxidant and anti-inflammatory compounds.  See below for Flavonoids explained for more information on these.

Antioxidant Activity of Enzogenol

Enzogenol has been shown to be a very powerful antioxidant in various antioxidant activity tests. A study by Wood et al. (Food Chemistry 77, 2002, p155) has compared the antioxidant activity of Enzogenol with that of other natural extracts, vitamin C and catechin. The results shown in the graph below demonstrate that Enzogenol was the most powerful antioxidant tested in this study and that Enzogenol is dramatically more powerful than for example vitamin C.

Present data is graphed from Table 1. of Wood et al. The antioxidant activity was analysed as the ability to scavenge superoxide radicals in a hypoxanthin oxidase system using the NBT assay. Numbers from the table have been transformed for better graphical representation to shown the % protection at 0.5 ug/ml antioxidant concentration averaging the activity of the three tests done at different pH values.

Flavonoids – explained

Flavonoids are a group of plant compounds that we usually obtain from our diet as part of the vegetables and fruit we eat. These flavonoids are very important for our health because they are natural antioxidants and anti-inflammatories. Another good source of flavonoids is the bark of pine trees, which is why Enzogenol is extracted from the pine bark. Hence, Enzogenol is a highly concentrated mixture of these natural antioxidant and anti-inflammatory flavonoid compounds.

Diet and Health

Research has shown that a diet rich in fruits and vegetables has significant protective effects against many diseases including cancer, heart disease, Alzheimer and others. This is a well established fact that has been shown in over one hundred epidemiological studies on diet and health.

Flavonoids in Fruits and Vegetables

Much of the disease protection from eating lots of fruits and veggies is due to the plant nutrient compounds known as flavonoids.

There are many different flavonoids and their type and amount differs between the types and varieties of fruits and vegetables. According to the US database for flavonoid content of selected foods, the average amount of flavonoids in 100 g of vegetables is 8.2 mg (based on 59 types of unprocessed/raw vegetables), and 100 g of fruit contain 20.9 mg of these goodies (based on 30 types of commonly available fresh fruit).

Role of Flavonoids in our Body

One important role that flavonoids play in our diet is their natural function as antioxidants. We live in a highly oxidative environment and many processes in our body produce more oxidants, also known as free radicals. Our bodies own antioxidant defence mechanisms are unfortunately not perfect and, consequently, oxidative damage to the building blocks of our body occurs all the time. Research has shown that oxidative damage contributes to many diseases including cancer, heart disease, Alzheimer, and most chronic diseases, and accumulation of oxidative damage plays an important role in the aging process. Therefore, it is important to protect ourselves against oxidative damage as best as we can.

Best Sources of Flavonoids

Apart from fruits and vegetables that are part of our general diet there are also other sources of flavonoids in nature that we usually do not utilise. One such source is tree bark and, in particular, the bark of pine trees. This explains why tree bark has featured prominently in many traditional folk medicines for hundreds of years.

Introducing ENZO Professional® and Enzogenol®

ENZO Professional is a practitioner only product, meaning it can only be recommended to you by a practitioner.  ENZO Professional contains a highly concentrated source of flavonoids containing 240 mg of Enzogenol pine bark extract in each capsule.  If you are interested in finding out more about this product, contact us by phoning 0800 HEALTH (0800 432 584).

You can purchase the retail product Enzogenol, a 100% natural flavonoid extract produced in New Zealand from the bark of New Zealand grown Pinus Radiata trees.  Each capsule contains 120mg.  The unique, high potency combination of flavonoids in Enzogenol is extracted from the tree bark with a specialised pure-water extraction method. This method maintains the full activity and integrity of the flavonoid compounds ensuring the high potency of ENZO Professional.

Read more information about the benefits of Enzogenol and Brain Injury and Enzogenol and Migraines

3 responses to “Enzogenol, The High Dose Flavonoid Antioxidant Formula”

  1. wait for your reply says:

    Dear Sirs:
    First thank you for your time to reading my email, this is jessica from china, in my hometwon, we have so many gingko trees, as well as leaves, nuts of gingko ,their quality is good with low price, hope you can give us some chance to have cooperation or introduce some company who need gingko to us,thank you in advance, i really hope to find some good buyer for the local.

    Best regards


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